Seeing our furry friends in pain from arthritis or after surgery can be really tough for dog owners. To help them feel better, vets often give special medicine to ease their pain and swelling. One popular medicine is called carprofen. While it can be very helpful, it’s important for pet owners to know how to use it safely and what side effects might happen. This article will explain what carprofen is, how it works, and the side effects to keep an eye on, in a way that’s simple and easy to understand.
What is Carprofen and How Does It Work?
Carprofen is a special medicine for dogs that helps with pain and swelling. You might know it as Rimadyl®, Novox®, or Vetprofen®. It is often used for older dogs with arthritis, which makes their joints hurt, and it can also help after they have surgery.

To understand how carprofen helps, it's good to know what causes pain and swelling in dogs. When a dog gets hurt or has something like arthritis, its body makes special chemicals called prostaglandins. These prostaglandins are made by enzymes known as cyclooxygenase, or COX for short. There are two main types of COX enzymes: COX-1 and COX-2.
COX-1 is like a helper that keeps our stomach lining healthy and helps our kidneys work well. COX-2, however, is mainly responsible for making chemicals that cause pain and swelling. Carprofen is made to focus more on blocking the COX-2 enzyme and less on COX-1. This means it can help reduce pain and swelling while causing fewer stomach problems compared to other pain medicines that aren't as picky.
Common and Mild Side Effects
Carprofen is usually safe for dogs, but like any medicine, it can cause some problems. The most common issues happen in the stomach. These problems are usually not very serious. To help keep your dog’s tummy happy, it's a good idea to give carprofen with food.

Some of the more common side effects include:
- Vomiting: Sometimes, dogs might throw up.
- Diarrhea: Dogs can also have loose stools when their tummies are upset.
- Less Hungry: You may see that your dog doesn't want to eat as much.
- Tiredness: Your dog might feel more sleepy than normal.
If you see any of these signs, please tell your vet. Most of the time, these side effects are not serious and can go away on their own, but it’s always good to let your vet know.
Serious, but Less Common, Side Effects
Though it's not common, carprofen can sometimes cause serious side effects. It's important for pet owners to know about these so they can quickly get help from a vet if needed. These serious reactions might affect your pet's kidneys, liver, or stomach.
Kidney-Related Side Effects:
If your dog starts drinking a lot more water or changes how often it goes to the bathroom, it might mean there’s a problem with its kidneys. Here are some things to watch for:
- Drinking more water than usual.
- Going to the bathroom more or less often.
- Sometimes, accidents in the house or changes in the color or smell of its pee.
Liver-Related Side Effects:
Some dogs might have liver problems after taking carprofen, especially in the first few weeks. Here are some signs to watch for:
- Yellow skin, gums, or the white part of their eyes (this is called jaundice).
- Ongoing vomiting or not wanting to eat.
Severe Gastrointestinal Issues:
What begins as a little stomach ache can sometimes turn into something worse. One major worry is getting stomach ulcers. Look out for:
- Stools that are black, sticky, or have blood in them.
- Vomit that has blood in it.
Other Rare Side Effects:
Sometimes, dogs might have strange symptoms like wobbling, trouble walking, or even shaking. They could also have allergic reactions, which can make their face swell up, cause hives, or make their skin itchy. But these are not very common.
Long-Term Use and Monitoring
For dogs that have ongoing problems like arthritis, taking carprofen for a long time can really help them feel better. If your dog is using carprofen for a while, the vet will probably want to check on them regularly to make sure the medicine is safe. This usually means doing blood tests to see how their liver and kidneys are doing. Often, the first test happens a few weeks after they start the medicine, and then they check again every three to six months.
The Importance of Veterinary Guidance
It's very important to only give your dog carprofen if a vet has prescribed it. Never give your dog human medicines like ibuprofen or naproxen because they can be very harmful. Your vet will decide how much carprofen your dog needs based on their weight and health. If your dog has health problems, like liver or kidney issues, the vet may say that carprofen is not safe for them.

If you ever give your dog too much carprofen by mistake, call your vet or an animal poison control center right away.
In summary, carprofen can really help your dog feel better by reducing pain and swelling, which can make their life more comfortable and active. It’s important to know about possible side effects and to talk to your veterinarian about it. They can help ensure your furry friend gets the most from this medicine safely. If you are worried about your dog and carprofen, just ask your vet—they are the best people to help with your pet’s health.